![]() ![]() "Nature designs all cells with survival mechanisms, and cancer cells are no exception," said Vogel, a professor and director of SMU's Center for Drug Discovery, Design and Delivery. ![]() The chemotherapy drug by itself was not effective in treating the drug-resistant cancer. The computational discovery was confirmed in the Wise-Vogel labs at SMU after aggressive micro-tumors cultured in the labs were treated with a solution carrying the molecules in combination with a classic chemotherapy drug. Wise and Vogel report the advancement in the Nature journal Scientific Reports. Now their effectiveness against specific cancers has been confirmed via wet-lab experiments, said biochemistry professors Pia Vogel and John G. The molecules were first discovered computationally via high-performance supercomputing.
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